Endocrine Abstracts

Background: MTC tends to metastasize early in the course of the disease affecting usually regional lymph nodes; in 7–23% of patients distant metastases may be present at diagnosis (common metastatic sites:liver, lungs, bone). We present two MTC cases with unusual metastases to the breast, pancreas and mandible.Case presentation: Patient No 1: a 48-year-old female was diagnosed with MTC in 1990. Total thyroidectomy was performed followed by neck diss...

Background: MTC tends to metastasize early in the course of the disease affecting usually regional lymph nodes; in 7–23% of patients distant metastases may be present at diagnosis (common metastatic sites:liver, lungs, bone). We present two MTC cases with unusual metastases to the breast, pancreas and mandible.Case presentation: Patient No 1A 48-year-old female was diagnosed with MTC in 1990. Total thyroidectomy was performed...

Introduction: Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumor of the gastrointestinal tract that consists of a dual adenocarcinomatous and neuroendocrine differentiation. The clinical behavior seems to be influenced by the neuroendocrine component. We report a patient with mixed adenoneuroendocrine carcinoma of cecum who presented 18 years after her initial diagnosis and treatment.Case report: A 59-year-old woman presented with a 3-month hist...

Introduction: In 30–50% of cases central diabetes insipidus (CDI) is idiopathic. Other causes include tumours, pituitary surgery, cranial trauma or infiltrative diseases. Long-term medical follow-up is crucial given that idiopathic CDI can be the earliest sign of an evolving process (inflammatory or tumoural).Case report: We report the case of a 23-year-old woman who presented with isolated polydipsia and polyuria. The diagnosis of isolated CDI was ...

Background: While the association between cigarette smoking and type 2 diabetes is established, the impact of smoking on developing gestational diabetes mellitus (GDM) remains controversial.Aim: To investigate whether maternal cigarette smoking during pregnancy is a risk factor for developing GDM.Methods: MEDLINE, Scopus, CENTRAL and Google Scholar databases were searched from inception to December 2022 to identify eligible origina...